{"title":"Cell \u0026 DNA Research","description":"","products":[{"product_id":"5-amino-1mq-5mg","title":"5 AMINO-1MQ 5MG","description":"\u003cp\u003e5-Amino 1mq – 5mg Vial\u003c\/p\u003e\n\n\u003cp\u003eResearch-Grade Synthetic Compound\u003cbr\u003e\nContents: 5mg of 5-Amino 1mq lyophilized powder\u003cbr\u003e\nForm: Freeze-Dried Powder\u003cbr\u003e\nPurity: ≥99% (HPLC Verified)\u003c\/p\u003e\n\n\u003cp\u003ePackaging: Supplied in a sterile, sealed vial with tamper-evident cap for laboratory use.\u003cbr\u003e\nNotice: This product is provided strictly for laboratory research use only. It is not intended for human or animal consumption, nor for diagnostic or therapeutic use.\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"One-time purchase","offer_id":51137696858345,"sku":"PS061-2","price":75.0,"currency_code":"PKR","in_stock":true},{"title":"20%  Discount Subscribe","offer_id":51137696891113,"sku":"PS061-1","price":60.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/5-Amino-1MQ-5mg.jpg?v=1778509456"},{"product_id":"nad-500mg","title":"NAD+ 500mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nNAD+ (Nicotinamide Adenine Dinucleotide) is a vital coenzyme found in every living cell, essential for energy production, DNA repair, and cellular function. It fluctuates between oxidized (NAD⁺) and reduced (NADH) forms, supporting mitochondrial health and longevity.\u003cbr\u003e\nKey Benefits of NAD+ Research:\u003cbr\u003e\n✔️ Boosts mitochondrial energy production\u003cbr\u003e\n✔️ Supports brain health and cognitive function\u003cbr\u003e\n✔️ Promotes longevity and cellular repair\u003cbr\u003e\n✔️ Enhances cardiovascular and metabolic health\u003cbr\u003e\n✔️ Reduces inflammation and supports immune function\u003cbr\u003e\nNAD+ is widely studied for its role in aging, neuroprotection, and metabolic disorders.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\n1. Mitochondrial Health \u0026amp; Energy Production\u003c\/p\u003e\n\n\u003cp\u003eNAD+ is essential for ATP production in mitochondria via the electron transport chain.\u003cbr\u003e\nDeclining NAD+ levels contribute to mitochondrial dysfunction, leading to fatigue, aging, and metabolic decline.\u003cbr\u003e\nRestoring NAD+ improves energy production and reduces oxidative stress.\u003cbr\u003e\nPotential application: Anti-aging, energy optimization, and mitochondrial health support.\u003c\/p\u003e\n\n\u003cp\u003e2. Brain Health \u0026amp; Cognitive Function\u003c\/p\u003e\n\n\u003cp\u003eNAD+ activates sirtuins and PGC-1α, key regulators of brain cell repair and neuroprotection.\u003cbr\u003e\nIt protects neurons from oxidative stress and inflammation, helping prevent Alzheimer’s, Parkinson’s, and cognitive decline.\u003cbr\u003e\nResearch suggests NAD+ enhances memory, learning, and focus in aging populations.\u003cbr\u003e\nPotential application: Brain function, neuroprotection, and cognitive longevity.\u003c\/p\u003e\n\n\u003cp\u003e3. Longevity \u0026amp; Anti-Aging\u003c\/p\u003e\n\n\u003cp\u003eNAD+ activates sirtuins (SIRT1 \u0026amp; SIRT3), enzymes linked to lifespan extension.\u003cbr\u003e\nIt maintains genomic stability by repairing DNA damage, slowing the aging process.\u003cbr\u003e\nNAD+ precursors delay age-related decline in muscle strength and vascular health.\u003cbr\u003e\nPotential application: Longevity, anti-aging, and cellular rejuvenation.\u003c\/p\u003e\n\n\u003cp\u003e4. Cardiovascular \u0026amp; Metabolic Health\u003c\/p\u003e\n\n\u003cp\u003eNAD+ supports blood vessel flexibility and prevents atherosclerosis.\u003cbr\u003e\nIt enhances insulin sensitivity, reducing the risk of Type 2 diabetes.\u003cbr\u003e\nHigher NAD+ levels protect against obesity and metabolic syndrome in animal studies.\u003cbr\u003e\nPotential application: Heart health, diabetes prevention, and metabolic balance.\u003c\/p\u003e\n\n\u003cp\u003e5. Inflammation \u0026amp; Immune Support\u003c\/p\u003e\n\n\u003cp\u003eNAD+ regulates inflammatory pathways, reducing chronic inflammation linked to metabolic disorders and autoimmune diseases.\u003cbr\u003e\nIt enhances immune function, helping fight infections and age-related immune decline.\u003cbr\u003e\nPotential application: Immune support and inflammation reduction.\u003c\/p\u003e\n\n\u003cp\u003e6. Addiction Recovery \u0026amp; Mood Regulation\u003c\/p\u003e\n\n\u003cp\u003eNAD+ levels are depleted in cases of chronic drug and alcohol use.\u003cbr\u003e\nSupplementation has been shown to reduce withdrawal symptoms and cravings.\u003cbr\u003e\nStudies suggest NAD+ supports mood stability and resilience against stress.\u003cbr\u003e\nPotential application: Addiction recovery and mental wellness.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₂₁H₂₇N₇O₁₄P₂\u003cbr\u003e\nMolecular Weight: 663.43 g\/mol\u003cbr\u003e\nCAS Number: 53-84-9\u003cbr\u003e\nSynonyms: Nicotinamide Adenine Dinucleotide, β-NAD, Endopride\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003eA. P. Gomes et al. Declining NAD+ disrupts nuclear-mitochondrial communication during aging. Cell (2013).\u003cbr\u003e\nS. Imai \u0026amp; L. Guarente. NAD+ and sirtuins in aging and disease. Trends Cell Biol. (2014).\u003cbr\u003e\nN. Sun, R. J. Youle \u0026amp; T. Finkel. The mitochondrial basis of aging. Mol. Cell (2016).\u003cbr\u003e\nR. T. Matthews et al. Coenzyme Q10 and NAD+ effects on brain mitochondrial function. PNAS (1998).\u003cbr\u003e\nC. Shan et al. Protective effects of NAD+ in Parkinson’s disease models. Prog. Neuropsychopharmacol. Biol. Psychiatry (2019).\u003cbr\u003e\nD. C. Maddison \u0026amp; F. Giorgini. The kynurenine pathway and neurodegeneration. Semin. Cell Dev. Biol. (2015).\u003cbr\u003e\nA. Garten et al. Roles of NAMPT and NAD+ metabolism in health and disease. Nat. Rev. Endocrinol. (2015).\u003cbr\u003e\nS. Yamaguchi \u0026amp; J. Yoshino. Adipose tissue NAD+ in obesity and insulin resistance. BioEssays (2017).\u003cbr\u003e\nD. Stipp. Beyond Resveratrol: The Anti-Aging NAD+ Fad. Scientific American (2019).\u003cbr\u003e\nS. Imai. NAD World 2.0: Systemic Regulation of Aging and Longevity. npj Systems Biology and Applications(2016).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989560365289,"sku":"PS061","price":75.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/NAD-500mg-scaled.jpg?v=1778509465"},{"product_id":"glutathione-gsh-1500mg","title":"Glutathione (GSH) 1500mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nL-Glutathione (GSH) is a powerful antioxidant and detoxifier that protects cells from oxidative stress, supports immune health, and plays a key role in anti-aging. It is a tripeptide composed of cysteine, glutamate, and glycine, essential for maintaining cellular redox balance and detoxification.\u003cbr\u003e\nKey Benefits of L-Glutathione Research:\u003cbr\u003e\n✔️ Supports brain health and reduces neurodegenerative risk\u003cbr\u003e\n✔️ Protects cartilage and joints from oxidative damage\u003cbr\u003e\n✔️ Enhances immune system function\u003cbr\u003e\n✔️ Improves skin health and brightens complexion\u003cbr\u003e\n✔️ Aids liver detoxification and heavy metal removal\u003cbr\u003e\nGSH is widely studied in longevity research, immune function, and chronic disease prevention.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\n1. Neuroprotection \u0026amp; Brain Health\u003c\/p\u003e\n\n\u003cp\u003eL-Glutathione shields neurons from oxidative stress, reducing the risk of neurodegenerative diseases like Alzheimer’s and Parkinson’s.\u003cbr\u003e\nLow GSH levels correlate with cognitive decline and increased oxidative brain damage.\u003cbr\u003e\nPotential application: Brain health support, cognitive enhancement, and neuroprotection.\u003c\/p\u003e\n\n\u003cp\u003e2. Cartilage \u0026amp; Joint Health\u003c\/p\u003e\n\n\u003cp\u003eGSH plays a role in cartilage regeneration and protects against osteoporosis and osteoarthritis.\u003cbr\u003e\nIt regulates inflammation and oxidative stress, preventing joint degeneration.\u003cbr\u003e\nPotential application: Joint health, arthritis prevention, and cartilage repair.\u003c\/p\u003e\n\n\u003cp\u003e3. Eye Health \u0026amp; Vision Protection\u003c\/p\u003e\n\n\u003cp\u003eGlutathione is present in high concentrations in the eye, particularly in the retina and lens.\u003cbr\u003e\nIt prevents cataracts and age-related macular degeneration (AMD) by neutralizing free radicals and UV damage.\u003cbr\u003e\nPotential application: Vision preservation and eye disease prevention.\u003c\/p\u003e\n\n\u003cp\u003e4. Immune System Enhancement\u003c\/p\u003e\n\n\u003cp\u003eGSH is critical for T-cell function and white blood cell activation, boosting immune defense.\u003cbr\u003e\nIt has been studied for its role in improving immune response in HIV and viral infections.\u003cbr\u003e\nPotential application: Immune support and infection prevention.\u003c\/p\u003e\n\n\u003cp\u003e5. Skin Health \u0026amp; Anti-Aging\u003c\/p\u003e\n\n\u003cp\u003eGlutathione reduces oxidative stress, promoting youthful skin, improved elasticity, and reduced wrinkles.\u003cbr\u003e\n**It lightens pigmentation by inhibiting melanin production, resulting in a brighter, more even complexion.\u003cbr\u003e\nPotential application: Skin rejuvenation, anti-aging, and hyperpigmentation reduction.\u003c\/p\u003e\n\n\u003cp\u003e6. Liver Detoxification \u0026amp; Heavy Metal Removal\u003c\/p\u003e\n\n\u003cp\u003eL-Glutathione is essential for detoxifying harmful toxins, including heavy metals, alcohol, and environmental pollutants.\u003cbr\u003e\nIt enhances liver function and prevents oxidative liver damage.\u003cbr\u003e\nPotential application: Liver detoxification, alcohol recovery, and toxin elimination.\u003c\/p\u003e\n\n\u003cp\u003e7. Oxidative Stress \u0026amp; Inflammation Control\u003c\/p\u003e\n\n\u003cp\u003eGSH neutralizes harmful free radicals that contribute to chronic inflammation, aging, and disease progression.\u003cbr\u003e\nLow GSH levels are associated with diabetes, cardiovascular disease, and metabolic disorders.\u003cbr\u003e\nPotential application: Inflammation reduction and metabolic health support.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eAmino Acid Sequence: γ-L-Glutamyl-L-cysteinyl-glycine\u003cbr\u003e\nMolecular Formula: C₁₀H₁₇N₃O₆S\u003cbr\u003e\nMolecular Weight: 307.33 g\/mol\u003cbr\u003e\nCAS Registry Number: 170-18-8\u003cbr\u003e\nSynonyms: GSH, Glutathione, Isethion\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003eH. J. Forman et al. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol. Aspects Med. (2009).\u003cbr\u003e\nG. Teskey et al. Glutathione as a Marker for Human Disease. Adv. Clin. Chem. (2018).\u003cbr\u003e\nS. Tsunoda et al. Protein folding and glutathione depletion in the endoplasmic reticulum. eLife (2014).\u003cbr\u003e\nJ. H. Wu \u0026amp; G. Batist. Glutathione and therapeutic potentials. Biochim. Biophys. Acta (2013).\u003cbr\u003e\nT. S. Nagapan et al. L-Glutathione prevents UVB-induced melanogenesis and oxidative stress. Exp. Anim. (2019).\u003cbr\u003e\nA. Bansal \u0026amp; M. C. Simon. Glutathione metabolism in cancer progression. J. Cell Biol. (2018).\u003cbr\u003e\nP. Maher. The effects of stress and aging on glutathione metabolism. Ageing Res. Rev. (2005).\u003cbr\u003e\nV. N. Reddy. Glutathione and its function in the lens. Exp. Eye Res. (1990).\u003cbr\u003e\nS. Weschawalit et al. Glutathione’s anti-aging and antimelanogenic effects. Clin. Cosmet. Investig. Dermatol. (2017).\u003cbr\u003e\nW. Dröge \u0026amp; R. Breitkreutz. Glutathione and immune function. Proc. Nutr. Soc. (2000).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989560430825,"sku":"PS059","price":85.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/L-GLUTATHION-GSH-1500MG-scaled.jpg?v=1778509466"},{"product_id":"mots-c-40mg","title":"MOTS-C 40mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nMOTS-c is a mitochondria-derived peptide (MDP) composed of 16 amino acids that plays a critical role in metabolic regulation, mitochondrial function, and cellular stress response. Unlike traditional peptides, MOTS-c is synthesized within mitochondria and translocates to the nucleus, where it regulates gene expression related to energy metabolism and longevity.\u003cbr\u003e\nKey Benefits of MOTS-c Research:\u003cbr\u003e\n✔️ Enhances muscle metabolism and exercise capacity\u003cbr\u003e\n✔️ Promotes fat oxidation and prevents obesity\u003cbr\u003e\n✔️ Improves insulin sensitivity and helps prevent Type 2 diabetes\u003cbr\u003e\n✔️ Protects against age-related diseases and enhances longevity\u003cbr\u003e\n✔️ Supports cardiovascular and bone health\u003cbr\u003e\nMOTS-c is being actively studied in metabolic disorders, aging research, and mitochondrial medicine.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\n1. Muscle Metabolism \u0026amp; Exercise Performance\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c enhances AMPK activation, improving glucose uptake in muscle tissue.\u003cbr\u003e\nStudies in mice show that MOTS-c increases endurance and muscle recovery post-exercise.\u003cbr\u003e\nPotential application: Exercise enhancement, muscle recovery, and metabolic health support.\u003c\/p\u003e\n\n\u003cp\u003e2. Fat Metabolism \u0026amp; Obesity Prevention\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c stimulates brown fat activation, promoting fat oxidation over storage.\u003cbr\u003e\nResearch indicates that MOTS-c supplementation prevents adipose tissue dysfunction and white fat accumulation.\u003cbr\u003e\nPotential application: Obesity treatment, fat metabolism regulation, and ketogenic diet support.\u003c\/p\u003e\n\n\u003cp\u003e3. Insulin Sensitivity \u0026amp; Diabetes Prevention\u003c\/p\u003e\n\n\u003cp\u003eLow MOTS-c levels are correlated with insulin resistance, particularly in obese individuals.\u003cbr\u003e\nMOTS-c supplementation enhances glucose metabolism and insulin sensitivity, making it a potential therapy for Type 2 diabetes.\u003cbr\u003e\nPotential application: Diabetes prevention, metabolic syndrome treatment, and insulin resistance improvement.\u003c\/p\u003e\n\n\u003cp\u003e4. Longevity \u0026amp; Aging Research\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c levels decline with age, and genetic studies link its variants to exceptional longevity (especially in Japanese centenarians).\u003cbr\u003e\nMOTS-c supplementation has been associated with improved mitochondrial function and protection against age-related diseases.\u003cbr\u003e\nPotential application: Longevity enhancement, anti-aging therapy, and mitochondrial function support.\u003c\/p\u003e\n\n\u003cp\u003e5. Cardiovascular Health\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c improves endothelial function, reducing inflammation and oxidative stress in blood vessels.\u003cbr\u003e\nClinical research shows lower MOTS-c levels correlate with a higher risk of coronary artery disease.\u003cbr\u003e\nPotential application: Cardiovascular disease prevention, blood vessel protection, and heart health improvement.\u003c\/p\u003e\n\n\u003cp\u003e6. Bone Health \u0026amp; Osteoporosis Prevention\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c activates the TGF-β\/SMAD signaling pathway, stimulating osteoblast activity and Type I collagen production.\u003cbr\u003e\nStudies suggest that MOTS-c enhances bone density and reduces fracture risk.\u003cbr\u003e\nPotential application: Osteoporosis prevention and bone regeneration therapy.\u003c\/p\u003e\n\n\u003cp\u003e7. Metabolic Stress \u0026amp; Mitochondrial Function\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c acts as a mitochondrial stress response peptide, regulating nuclear gene expression to counteract metabolic dysfunction.\u003cbr\u003e\nIt influences glucose metabolism and antioxidant defense, offering protection against metabolic diseases.\u003cbr\u003e\nPotential application: Mitochondrial medicine, metabolic disease treatment, and cellular stress response regulation.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eAmino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg\u003cbr\u003e\nMolecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂\u003cbr\u003e\nMolecular Weight: 2174.64 g\/mol\u003cbr\u003e\nCAS Registry Number: 1627580-64-6\u003cbr\u003e\nSynonyms: Mitochondrial Open Reading Frame of the 12S rRNA-c (MT-RNR1), MOTS-c Peptide\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003eC. Lee, K. H. Kim, \u0026amp; P. Cohen. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radic. Biol. Med. (2016).\u003cbr\u003e\nH. Lu et al. MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. J. Mol. Med. Berl. Ger. (2019).\u003cbr\u003e\nK. H. Kim et al. MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress. Cell Metab. (2018).\u003cbr\u003e\nS.-J. Kim et al. MOTS-c enhances insulin sensitivity and regulates plasma metabolites. Physiol. Rep. (2019).\u003cbr\u003e\nL. R. Cataldo et al. Plasma MOTS-c levels are associated with insulin sensitivity in lean but not obese individuals. J. Investig. Med. (2018).\u003cbr\u003e\nN. Che et al. MOTS-c improves osteoporosis by promoting Type I collagen synthesis in osteoblasts via TGF-β\/SMAD signaling pathway. Eur. Rev. Med. Pharmacol. Sci. (2019).\u003cbr\u003e\nN. Fuku et al. MOTS-c as a key player in exceptional longevity. Aging Cell (2015).\u003cbr\u003e\nQ. Qin et al. Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction. Int. J. Cardiol. (2018).\u003cbr\u003e\nY. Yang et al. MOTS-c’s role in cardiovascular disease: Recent updates. Biomed. Pharmacother. (2019).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989560496361,"sku":"PS057","price":160.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/mots-c-40mg-scaled.jpg?v=1778509468"},{"product_id":"mots-c-10mg","title":"MOTS-C 10mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nMOTS-c is a mitochondria-derived peptide (MDP) composed of 16 amino acids that plays a critical role in metabolic regulation, mitochondrial function, and cellular stress response. Unlike traditional peptides, MOTS-c is synthesized within mitochondria and translocates to the nucleus, where it regulates gene expression related to energy metabolism and longevity.\u003cbr\u003e\nKey Benefits of MOTS-c Research:\u003cbr\u003e\n✔️ Enhances muscle metabolism and exercise capacity\u003cbr\u003e\n✔️ Promotes fat oxidation and prevents obesity\u003cbr\u003e\n✔️ Improves insulin sensitivity and helps prevent Type 2 diabetes\u003cbr\u003e\n✔️ Protects against age-related diseases and enhances longevity\u003cbr\u003e\n✔️ Supports cardiovascular and bone health\u003cbr\u003e\nMOTS-c is being actively studied in metabolic disorders, aging research, and mitochondrial medicine.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\n1. Muscle Metabolism \u0026amp; Exercise Performance\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c enhances AMPK activation, improving glucose uptake in muscle tissue.\u003cbr\u003e\nStudies in mice show that MOTS-c increases endurance and muscle recovery post-exercise.\u003cbr\u003e\nPotential application: Exercise enhancement, muscle recovery, and metabolic health support.\u003c\/p\u003e\n\n\u003cp\u003e2. Fat Metabolism \u0026amp; Obesity Prevention\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c stimulates brown fat activation, promoting fat oxidation over storage.\u003cbr\u003e\nResearch indicates that MOTS-c supplementation prevents adipose tissue dysfunction and white fat accumulation.\u003cbr\u003e\nPotential application: Obesity treatment, fat metabolism regulation, and ketogenic diet support.\u003c\/p\u003e\n\n\u003cp\u003e3. Insulin Sensitivity \u0026amp; Diabetes Prevention\u003c\/p\u003e\n\n\u003cp\u003eLow MOTS-c levels are correlated with insulin resistance, particularly in obese individuals.\u003cbr\u003e\nMOTS-c supplementation enhances glucose metabolism and insulin sensitivity, making it a potential therapy for Type 2 diabetes.\u003cbr\u003e\nPotential application: Diabetes prevention, metabolic syndrome treatment, and insulin resistance improvement.\u003c\/p\u003e\n\n\u003cp\u003e4. Longevity \u0026amp; Aging Research\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c levels decline with age, and genetic studies link its variants to exceptional longevity (especially in Japanese centenarians).\u003cbr\u003e\nMOTS-c supplementation has been associated with improved mitochondrial function and protection against age-related diseases.\u003cbr\u003e\nPotential application: Longevity enhancement, anti-aging therapy, and mitochondrial function support.\u003c\/p\u003e\n\n\u003cp\u003e5. Cardiovascular Health\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c improves endothelial function, reducing inflammation and oxidative stress in blood vessels.\u003cbr\u003e\nClinical research shows lower MOTS-c levels correlate with a higher risk of coronary artery disease.\u003cbr\u003e\nPotential application: Cardiovascular disease prevention, blood vessel protection, and heart health improvement.\u003c\/p\u003e\n\n\u003cp\u003e6. Bone Health \u0026amp; Osteoporosis Prevention\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c activates the TGF-β\/SMAD signaling pathway, stimulating osteoblast activity and Type I collagen production.\u003cbr\u003e\nStudies suggest that MOTS-c enhances bone density and reduces fracture risk.\u003cbr\u003e\nPotential application: Osteoporosis prevention and bone regeneration therapy.\u003c\/p\u003e\n\n\u003cp\u003e7. Metabolic Stress \u0026amp; Mitochondrial Function\u003c\/p\u003e\n\n\u003cp\u003eMOTS-c acts as a mitochondrial stress response peptide, regulating nuclear gene expression to counteract metabolic dysfunction.\u003cbr\u003e\nIt influences glucose metabolism and antioxidant defense, offering protection against metabolic diseases.\u003cbr\u003e\nPotential application: Mitochondrial medicine, metabolic disease treatment, and cellular stress response regulation.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eAmino Acid Sequence: Met-Arg-Trp-Gln-Glu-Met-Gly-Tyr-Ile-Phe-Tyr-Pro-Arg-Lys-Leu-Arg\u003cbr\u003e\nMolecular Formula: C₁₀₁H₁₅₂N₂₈O₂₂S₂\u003cbr\u003e\nMolecular Weight: 2174.64 g\/mol\u003cbr\u003e\nCAS Registry Number: 1627580-64-6\u003cbr\u003e\nSynonyms: Mitochondrial Open Reading Frame of the 12S rRNA-c (MT-RNR1), MOTS-c Peptide\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003eC. Lee, K. H. Kim, \u0026amp; P. Cohen. MOTS-c: A novel mitochondrial-derived peptide regulating muscle and fat metabolism. Free Radic. Biol. Med. (2016).\u003cbr\u003e\nH. Lu et al. MOTS-c peptide regulates adipose homeostasis to prevent ovariectomy-induced metabolic dysfunction. J. Mol. Med. Berl. Ger. (2019).\u003cbr\u003e\nK. H. Kim et al. MOTS-c translocates to the nucleus to regulate nuclear gene expression in response to metabolic stress. Cell Metab. (2018).\u003cbr\u003e\nS.-J. Kim et al. MOTS-c enhances insulin sensitivity and regulates plasma metabolites. Physiol. Rep. (2019).\u003cbr\u003e\nL. R. Cataldo et al. Plasma MOTS-c levels are associated with insulin sensitivity in lean but not obese individuals. J. Investig. Med. (2018).\u003cbr\u003e\nN. Che et al. MOTS-c improves osteoporosis by promoting Type I collagen synthesis in osteoblasts via TGF-β\/SMAD signaling pathway. Eur. Rev. Med. Pharmacol. Sci. (2019).\u003cbr\u003e\nN. Fuku et al. MOTS-c as a key player in exceptional longevity. Aging Cell (2015).\u003cbr\u003e\nQ. Qin et al. Downregulation of circulating MOTS-c levels in patients with coronary endothelial dysfunction. Int. J. Cardiol. (2018).\u003cbr\u003e\nY. Yang et al. MOTS-c’s role in cardiovascular disease: Recent updates. Biomed. Pharmacother. (2019).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989560529129,"sku":"PS056","price":75.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/mots-c-10mg-scaled.jpg?v=1778509469"},{"product_id":"ghk-cu-100mg","title":"GHK-Cu 100mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nGHK-Cu is a naturally occurring peptide found in human blood plasma, urine, and saliva. Research suggests that this copper-binding peptide plays a crucial role in wound healing, immune support, and skin health by promoting collagen production, fibroblast activation, and blood vessel formation.\u003cbr\u003e\nAdditionally, GHK-Cu functions as a regulatory signal following tissue injury, helping to reduce inflammation and promote tissue repair. It also exhibits strong antioxidant properties, which aid in protecting cells from free-radical damage.\u003cbr\u003e\nDue to these effects, GHK-Cu has gained significant interest in anti-aging, skin rejuvenation, and regenerative medicine.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\nGHK-Cu and Skin Regeneration\u003cbr\u003e\nGHK-Cu plays an essential role in skin healing and repair. Studies show that it:\u003c\/p\u003e\n\n\u003cp\u003eStimulates collagen production while also enhancing its breakdown for remodeling.\u003cbr\u003e\nBoosts glycosaminoglycan synthesis, which improves skin hydration and elasticity.\u003cbr\u003e\nIncreases fibroblast activity, accelerating the healing process.\u003cbr\u003e\nPromotes angiogenesis (formation of new blood vessels) at wound sites.\u003c\/p\u003e\n\n\u003cp\u003eBecause of these regenerative properties, GHK-Cu is widely used in skincare and cosmetic formulations. Research indicates it can:\u003c\/p\u003e\n\n\u003cp\u003eEnhance skin elasticity, firmness, and hydration.\u003cbr\u003e\nReduce sun damage, hyperpigmentation, and oxidative stress.\u003cbr\u003e\nDiminish fine lines, wrinkles, and other signs of aging.\u003c\/p\u003e\n\n\u003cp\u003eAnimal studies have demonstrated that GHK-Cu accelerates wound healing by 33%, particularly in burn injuries, by enhancing blood vessel formation and tissue repair.\u003cbr\u003e\nGHK-Cu’s Antimicrobial Effects\u003cbr\u003e\nInfections can significantly delay wound healing. Research suggests that GHK-Cu combined with fatty acids creates a potent antimicrobial compound that combats bacteria and fungi responsible for wound infections.\u003cbr\u003e\nIn clinical studies involving diabetic patients, GHK-Cu:\u003c\/p\u003e\n\n\u003cp\u003eIncreased wound closure rates by 40%.\u003cbr\u003e\nReduced infection rates by 27% compared to conventional treatments.\u003c\/p\u003e\n\n\u003cp\u003eGHK-Cu and Cognitive Function\u003cbr\u003e\nGHK-Cu may also play a role in neuroprotection and brain health, with potential implications for Alzheimer’s disease and cognitive decline. Studies indicate it can:\u003c\/p\u003e\n\n\u003cp\u003ePromote nerve outgrowth and regeneration.\u003cbr\u003e\nImprove blood vessel formation (angiogenesis) in neural tissues.\u003cbr\u003e\nReduce inflammation in brain cells, which is linked to age-related cognitive decline.\u003cbr\u003e\nReset pathological gene expression associated with aging brains.\u003c\/p\u003e\n\n\u003cp\u003eInterestingly, GHK-Cu levels decline significantly with age, which has led researchers to explore its connection to neurodegeneration and cognitive disorders.\u003cbr\u003e\nGHK-Cu and Chemotherapy Side Effects\u003cbr\u003e\nResearch in animal models suggests that GHK-Cu may protect against chemotherapy-induced lung damage:\u003c\/p\u003e\n\n\u003cp\u003eA mouse study showed that GHK-Cu prevented lung fibrosis caused by the chemotherapy drug bleomycin.\u003cbr\u003e\nIt appears to regulate TNF-alpha and IL-6, two inflammatory molecules involved in lung injury and fibrosis.\u003c\/p\u003e\n\n\u003cp\u003eIn acute respiratory distress syndrome (ARDS) models, GHK-Cu reduced inflammation, fibrosis, and oxidative stress, suggesting potential applications in lung disease management.\u003cbr\u003e\nGHK-Cu and Pain Management\u003cbr\u003e\nAnimal research suggests that GHK-Cu may act as a natural pain reliever by influencing L-lysine and L-arginine levels, two amino acids involved in pain modulation.\u003cbr\u003e\nThese findings indicate that GHK-Cu could be a potential alternative to opioids and NSAIDs for managing pain without harmful side effects.\u003cbr\u003e\nSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₁₄H₂₃CuN₆O₄\u003cbr\u003e\nMolecular Weight: 340.38 g\/mol\u003cbr\u003e\nAmino Acid Sequence: Gly-His-Lys.Cu.xHAc\u003cbr\u003e\nCAS Registry Number: 89030-95-5\u003cbr\u003e\nPubChem Identifier: 73587\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003ePickart L., Vasquez-Soltero J. M., Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International (2015).\u003cbr\u003e\nGruchlik A., Chodurek E., Dzierzewicz Z. Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts. Acta Pol. Pharm. (2014).\u003cbr\u003e\nPickart L., Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences (2018).\u003cbr\u003e\nWang X. et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regeneration (2017).\u003cbr\u003e\nKukowska M., Kukowska-Kaszuba M., Dzierzbicka K. In vitro studies of antimicrobial activity of Gly-His-Lys conjugates. Bioorganic \u0026amp; Medicinal Chemistry Letters (2015).\u003cbr\u003e\nMulder G. D. et al. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regeneration (1994).\u003cbr\u003e\nCanapp S. O. et al. The effect of topical tripeptide-copper complex on healing of ischemic open wounds.Veterinary Surgery (2003).\u003cbr\u003e\nPickart L., Vasquez-Soltero J. M., Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sciences (2017).\u003cbr\u003e\nZhang H., Wang Y., He Z. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p\/VEGFA Pathway. Frontiers in Neuroscience (2018).\u003cbr\u003e\nZhou X-M. et al. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1\/Smad-Mediated Epithelial-to-Mesenchymal Transition. Frontiers in Pharmacology (2017).\u003cbr\u003e\nPark J-R., Lee H., Kim S-I., Yang S-R. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget (2016).\u003cbr\u003e\nSever’yanova L. A., Dolgintsev M. E. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats. Bulletin of Experimental Biology and Medicine (2017).\u003cbr\u003e\nSever’yanova L. A., Plotnikov D. V. Binding of Glyprolines to L-Arginine Inverts Its Analgesic and Antiagressogenic Effects. Bulletin of Experimental Biology and Medicine (2018).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989561413865,"sku":"PS023","price":100.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/WhatsApp_Image_2026-06-11_at_11.16.33_AM_1.jpg?v=1781542776"},{"product_id":"ghk-cu-50mg","title":"GHK-Cu 50mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nGHK-Cu is a naturally occurring peptide found in human blood plasma, urine, and saliva. Research suggests that this copper-binding peptide plays a crucial role in wound healing, immune support, and skin health by promoting collagen production, fibroblast activation, and blood vessel formation.\u003cbr\u003e\nAdditionally, GHK-Cu functions as a regulatory signal following tissue injury, helping to reduce inflammation and promote tissue repair. It also exhibits strong antioxidant properties, which aid in protecting cells from free-radical damage.\u003cbr\u003e\nDue to these effects, GHK-Cu has gained significant interest in anti-aging, skin rejuvenation, and regenerative medicine.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\nGHK-Cu and Skin Regeneration\u003cbr\u003e\nGHK-Cu plays an essential role in skin healing and repair. Studies show that it:\u003c\/p\u003e\n\n\u003cp\u003eStimulates collagen production while also enhancing its breakdown for remodeling.\u003cbr\u003e\nBoosts glycosaminoglycan synthesis, which improves skin hydration and elasticity.\u003cbr\u003e\nIncreases fibroblast activity, accelerating the healing process.\u003cbr\u003e\nPromotes angiogenesis (formation of new blood vessels) at wound sites.\u003c\/p\u003e\n\n\u003cp\u003eBecause of these regenerative properties, GHK-Cu is widely used in skincare and cosmetic formulations. Research indicates it can:\u003c\/p\u003e\n\n\u003cp\u003eEnhance skin elasticity, firmness, and hydration.\u003cbr\u003e\nReduce sun damage, hyperpigmentation, and oxidative stress.\u003cbr\u003e\nDiminish fine lines, wrinkles, and other signs of aging.\u003c\/p\u003e\n\n\u003cp\u003eAnimal studies have demonstrated that GHK-Cu accelerates wound healing by 33%, particularly in burn injuries, by enhancing blood vessel formation and tissue repair.\u003cbr\u003e\nGHK-Cu’s Antimicrobial Effects\u003cbr\u003e\nInfections can significantly delay wound healing. Research suggests that GHK-Cu combined with fatty acids creates a potent antimicrobial compound that combats bacteria and fungi responsible for wound infections.\u003cbr\u003e\nIn clinical studies involving diabetic patients, GHK-Cu:\u003c\/p\u003e\n\n\u003cp\u003eIncreased wound closure rates by 40%.\u003cbr\u003e\nReduced infection rates by 27% compared to conventional treatments.\u003c\/p\u003e\n\n\u003cp\u003eGHK-Cu and Cognitive Function\u003cbr\u003e\nGHK-Cu may also play a role in neuroprotection and brain health, with potential implications for Alzheimer’s disease and cognitive decline. Studies indicate it can:\u003c\/p\u003e\n\n\u003cp\u003ePromote nerve outgrowth and regeneration.\u003cbr\u003e\nImprove blood vessel formation (angiogenesis) in neural tissues.\u003cbr\u003e\nReduce inflammation in brain cells, which is linked to age-related cognitive decline.\u003cbr\u003e\nReset pathological gene expression associated with aging brains.\u003c\/p\u003e\n\n\u003cp\u003eInterestingly, GHK-Cu levels decline significantly with age, which has led researchers to explore its connection to neurodegeneration and cognitive disorders.\u003cbr\u003e\nGHK-Cu and Chemotherapy Side Effects\u003cbr\u003e\nResearch in animal models suggests that GHK-Cu may protect against chemotherapy-induced lung damage:\u003c\/p\u003e\n\n\u003cp\u003eA mouse study showed that GHK-Cu prevented lung fibrosis caused by the chemotherapy drug bleomycin.\u003cbr\u003e\nIt appears to regulate TNF-alpha and IL-6, two inflammatory molecules involved in lung injury and fibrosis.\u003c\/p\u003e\n\n\u003cp\u003eIn acute respiratory distress syndrome (ARDS) models, GHK-Cu reduced inflammation, fibrosis, and oxidative stress, suggesting potential applications in lung disease management.\u003cbr\u003e\nGHK-Cu and Pain Management\u003cbr\u003e\nAnimal research suggests that GHK-Cu may act as a natural pain reliever by influencing L-lysine and L-arginine levels, two amino acids involved in pain modulation.\u003cbr\u003e\nThese findings indicate that GHK-Cu could be a potential alternative to opioids and NSAIDs for managing pain without harmful side effects.\u003cbr\u003e\nSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₁₄H₂₃CuN₆O₄\u003cbr\u003e\nMolecular Weight: 340.38 g\/mol\u003cbr\u003e\nAmino Acid Sequence: Gly-His-Lys.Cu.xHAc\u003cbr\u003e\nCAS Registry Number: 89030-95-5\u003cbr\u003e\nPubChem Identifier: 73587\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003ePickart L., Vasquez-Soltero J. M., Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International (2015).\u003cbr\u003e\nGruchlik A., Chodurek E., Dzierzewicz Z. Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts. Acta Pol. Pharm. (2014).\u003cbr\u003e\nPickart L., Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences (2018).\u003cbr\u003e\nWang X. et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regeneration (2017).\u003cbr\u003e\nKukowska M., Kukowska-Kaszuba M., Dzierzbicka K. In vitro studies of antimicrobial activity of Gly-His-Lys conjugates. Bioorganic \u0026amp; Medicinal Chemistry Letters (2015).\u003cbr\u003e\nMulder G. D. et al. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regeneration (1994).\u003cbr\u003e\nCanapp S. O. et al. The effect of topical tripeptide-copper complex on healing of ischemic open wounds.Veterinary Surgery (2003).\u003cbr\u003e\nPickart L., Vasquez-Soltero J. M., Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sciences (2017).\u003cbr\u003e\nZhang H., Wang Y., He Z. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p\/VEGFA Pathway. Frontiers in Neuroscience (2018).\u003cbr\u003e\nZhou X-M. et al. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1\/Smad-Mediated Epithelial-to-Mesenchymal Transition. Frontiers in Pharmacology (2017).\u003cbr\u003e\nPark J-R., Lee H., Kim S-I., Yang S-R. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget (2016).\u003cbr\u003e\nSever’yanova L. A., Dolgintsev M. E. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats. Bulletin of Experimental Biology and Medicine (2017).\u003cbr\u003e\nSever’yanova L. A., Plotnikov D. V. Binding of Glyprolines to L-Arginine Inverts Its Analgesic and Antiagressogenic Effects. Bulletin of Experimental Biology and Medicine (2018).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989561446633,"sku":"PS022","price":50.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/GHKcu-50MG-scaled.jpg?v=1778509495"},{"product_id":"ghk-cu-100mg-copy","title":"GHK-Cu 10mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nGHK-Cu is a naturally occurring peptide found in human blood plasma, urine, and saliva. Research suggests that this copper-binding peptide plays a crucial role in wound healing, immune support, and skin health by promoting collagen production, fibroblast activation, and blood vessel formation.\u003cbr\u003e\nAdditionally, GHK-Cu functions as a regulatory signal following tissue injury, helping to reduce inflammation and promote tissue repair. It also exhibits strong antioxidant properties, which aid in protecting cells from free-radical damage.\u003cbr\u003e\nDue to these effects, GHK-Cu has gained significant interest in anti-aging, skin rejuvenation, and regenerative medicine.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\nGHK-Cu and Skin Regeneration\u003cbr\u003e\nGHK-Cu plays an essential role in skin healing and repair. Studies show that it:\u003c\/p\u003e\n\n\u003cp\u003eStimulates collagen production while also enhancing its breakdown for remodeling.\u003cbr\u003e\nBoosts glycosaminoglycan synthesis, which improves skin hydration and elasticity.\u003cbr\u003e\nIncreases fibroblast activity, accelerating the healing process.\u003cbr\u003e\nPromotes angiogenesis (formation of new blood vessels) at wound sites.\u003c\/p\u003e\n\n\u003cp\u003eBecause of these regenerative properties, GHK-Cu is widely used in skincare and cosmetic formulations. Research indicates it can:\u003c\/p\u003e\n\n\u003cp\u003eEnhance skin elasticity, firmness, and hydration.\u003cbr\u003e\nReduce sun damage, hyperpigmentation, and oxidative stress.\u003cbr\u003e\nDiminish fine lines, wrinkles, and other signs of aging.\u003c\/p\u003e\n\n\u003cp\u003eAnimal studies have demonstrated that GHK-Cu accelerates wound healing by 33%, particularly in burn injuries, by enhancing blood vessel formation and tissue repair.\u003cbr\u003e\nGHK-Cu’s Antimicrobial Effects\u003cbr\u003e\nInfections can significantly delay wound healing. Research suggests that GHK-Cu combined with fatty acids creates a potent antimicrobial compound that combats bacteria and fungi responsible for wound infections.\u003cbr\u003e\nIn clinical studies involving diabetic patients, GHK-Cu:\u003c\/p\u003e\n\n\u003cp\u003eIncreased wound closure rates by 40%.\u003cbr\u003e\nReduced infection rates by 27% compared to conventional treatments.\u003c\/p\u003e\n\n\u003cp\u003eGHK-Cu and Cognitive Function\u003cbr\u003e\nGHK-Cu may also play a role in neuroprotection and brain health, with potential implications for Alzheimer’s disease and cognitive decline. Studies indicate it can:\u003c\/p\u003e\n\n\u003cp\u003ePromote nerve outgrowth and regeneration.\u003cbr\u003e\nImprove blood vessel formation (angiogenesis) in neural tissues.\u003cbr\u003e\nReduce inflammation in brain cells, which is linked to age-related cognitive decline.\u003cbr\u003e\nReset pathological gene expression associated with aging brains.\u003c\/p\u003e\n\n\u003cp\u003eInterestingly, GHK-Cu levels decline significantly with age, which has led researchers to explore its connection to neurodegeneration and cognitive disorders.\u003cbr\u003e\nGHK-Cu and Chemotherapy Side Effects\u003cbr\u003e\nResearch in animal models suggests that GHK-Cu may protect against chemotherapy-induced lung damage:\u003c\/p\u003e\n\n\u003cp\u003eA mouse study showed that GHK-Cu prevented lung fibrosis caused by the chemotherapy drug bleomycin.\u003cbr\u003e\nIt appears to regulate TNF-alpha and IL-6, two inflammatory molecules involved in lung injury and fibrosis.\u003c\/p\u003e\n\n\u003cp\u003eIn acute respiratory distress syndrome (ARDS) models, GHK-Cu reduced inflammation, fibrosis, and oxidative stress, suggesting potential applications in lung disease management.\u003cbr\u003e\nGHK-Cu and Pain Management\u003cbr\u003e\nAnimal research suggests that GHK-Cu may act as a natural pain reliever by influencing L-lysine and L-arginine levels, two amino acids involved in pain modulation.\u003cbr\u003e\nThese findings indicate that GHK-Cu could be a potential alternative to opioids and NSAIDs for managing pain without harmful side effects.\u003cbr\u003e\nSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₁₄H₂₃CuN₆O₄\u003cbr\u003e\nMolecular Weight: 340.38 g\/mol\u003cbr\u003e\nAmino Acid Sequence: Gly-His-Lys.Cu.xHAc\u003cbr\u003e\nCAS Registry Number: 89030-95-5\u003cbr\u003e\nPubChem Identifier: 73587\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003ePickart L., Vasquez-Soltero J. M., Margolina A. GHK Peptide as a Natural Modulator of Multiple Cellular Pathways in Skin Regeneration. BioMed Research International (2015).\u003cbr\u003e\nGruchlik A., Chodurek E., Dzierzewicz Z. Effect of GLY-HIS-LYS and its copper complex on TGF-β secretion in normal human dermal fibroblasts. Acta Pol. Pharm. (2014).\u003cbr\u003e\nPickart L., Margolina A. Regenerative and Protective Actions of the GHK-Cu Peptide in the Light of the New Gene Data. International Journal of Molecular Sciences (2018).\u003cbr\u003e\nWang X. et al. GHK-Cu-liposomes accelerate scald wound healing in mice by promoting cell proliferation and angiogenesis. Wound Repair Regeneration (2017).\u003cbr\u003e\nKukowska M., Kukowska-Kaszuba M., Dzierzbicka K. In vitro studies of antimicrobial activity of Gly-His-Lys conjugates. Bioorganic \u0026amp; Medicinal Chemistry Letters (2015).\u003cbr\u003e\nMulder G. D. et al. Enhanced healing of ulcers in patients with diabetes by topical treatment with glycyl-l-histidyl-l-lysine copper. Wound Repair Regeneration (1994).\u003cbr\u003e\nCanapp S. O. et al. The effect of topical tripeptide-copper complex on healing of ischemic open wounds.Veterinary Surgery (2003).\u003cbr\u003e\nPickart L., Vasquez-Soltero J. M., Margolina A. The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline. Brain Sciences (2017).\u003cbr\u003e\nZhang H., Wang Y., He Z. Glycine-Histidine-Lysine (GHK) Alleviates Neuronal Apoptosis Due to Intracerebral Hemorrhage via the miR-339-5p\/VEGFA Pathway. Frontiers in Neuroscience (2018).\u003cbr\u003e\nZhou X-M. et al. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1\/Smad-Mediated Epithelial-to-Mesenchymal Transition. Frontiers in Pharmacology (2017).\u003cbr\u003e\nPark J-R., Lee H., Kim S-I., Yang S-R. The tri-peptide GHK-Cu complex ameliorates lipopolysaccharide-induced acute lung injury in mice. Oncotarget (2016).\u003cbr\u003e\nSever’yanova L. A., Dolgintsev M. E. Effects of Tripeptide Gly-His-Lys in Pain-Induced Aggressive-Defensive Behavior in Rats. Bulletin of Experimental Biology and Medicine (2017).\u003cbr\u003e\nSever’yanova L. A., Plotnikov D. V. Binding of Glyprolines to L-Arginine Inverts Its Analgesic and Antiagressogenic Effects. Bulletin of Experimental Biology and Medicine (2018).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":51277876232425,"sku":"PS023","price":100.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/WhatsApp_Image_2026-06-11_at_11.16.33_AM_1.jpg?v=1781542776"}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/collections\/Peptides_Verse_Collection_image_04_jpg.jpg?v=1779217049","url":"https:\/\/f1kjgr-r5.myshopify.com\/collections\/cell-dna-research.oembed","provider":"Peptides Verse","version":"1.0","type":"link"}