{"product_id":"igf-1-lr3-1mg","title":"IGF-1 LR3 .1mg","description":"\u003cp\u003eOVERVIEW\u003cbr\u003e\nIGF-1 LR3 (Insulin-Like Growth Factor-1 Long R3) is a synthetic modified form of IGF-1, designed to extend its biological activity by preventing binding to IGF-binding proteins. This modification makes IGF-1 LR3 up to 120 times longer-lasting than standard IGF-1, significantly enhancing its effects on cell growth, metabolism, and muscle repair.\u003cbr\u003e\nResearch suggests IGF-1 LR3 may:\u003c\/p\u003e\n\n\u003cp\u003eStimulate cell division and tissue growth, affecting muscles, bones, nerves, and vital organs.\u003cbr\u003e\nEnhance fat metabolism, leading to reduced adipose tissue and improved glucose regulation.\u003cbr\u003e\nSupport muscle repair and hypertrophy, by counteracting myostatin’s inhibitory effects.\u003cbr\u003e\nPromote longevity and cellular maintenance, by reducing age-related tissue degeneration.\u003cbr\u003e\nProtect against glucocorticoid-induced muscle loss, supporting muscle preservation in individuals undergoing corticosteroid therapy.\u003c\/p\u003e\n\n\u003cp\u003eDue to these properties, IGF-1 LR3 has been explored in muscle-wasting conditions, diabetes research, and anti-aging therapies.\u003cbr\u003e\nRESEARCH\u003cbr\u003e\nIGF-1 LR3 and Cell Growth\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 is a potent stimulator of cell division and proliferation.\u003cbr\u003e\nPrimarily affects muscles and bones, but also influences liver, kidney, nerve, skin, lung, and blood tissues.\u003cbr\u003e\nLonger circulation time compared to IGF-1, making it more effective in promoting cell maturation and tissue regeneration.\u003cbr\u003e\nPotential application: Regenerative medicine and muscle recovery.\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 and Fat Metabolism\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 binds to insulin receptors, enhancing glucose uptake in muscle, liver, and nerve cells.\u003cbr\u003e\nThis leads to lower blood sugar levels, triggering fat breakdown and a net decrease in adipose tissue.\u003cbr\u003e\nPotential application: Obesity management and diabetes therapy.\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 and Muscle Growth (Myostatin Inhibition)\u003c\/p\u003e\n\n\u003cp\u003eMyostatin is a natural inhibitor of muscle growth—IGF-1 LR3 blocks its effects, allowing enhanced muscle repair and hypertrophy.\u003cbr\u003e\nResearch suggests IGF-1 LR3 may be beneficial for conditions such as Duchenne Muscular Dystrophy (DMD) and muscle atrophy due to immobility or chronic illness.\u003cbr\u003e\nPotential application: Muscle-wasting disorder treatment and sports performance research.\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 and Longevity Research\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 supports tissue repair and maintenance, offering protective benefits against age-related decline.\u003cbr\u003e\nStudies in livestock models (cows and pigs) suggest IGF-1 LR3 can counteract cellular aging effects.\u003cbr\u003e\nOngoing research in mice explores IGF-1 LR3’s role in preventing dementia, muscle loss, and kidney disease.\u003cbr\u003e\nPotential application: Anti-aging and age-related disease prevention.\u003c\/p\u003e\n\n\u003cp\u003eIGF-1 LR3 and Glucocorticoid Protection\u003c\/p\u003e\n\n\u003cp\u003eGlucocorticoids are commonly used anti-inflammatory drugs, but long-term use can cause muscle wasting, fat gain, and bone density loss.\u003cbr\u003e\nIGF-1 LR3 counteracts these negative effects, allowing for more effective corticosteroid therapy with reduced side effects.\u003cbr\u003e\nPotential application: Muscle preservation in patients undergoing glucocorticoid therapy.\u003c\/p\u003e\n\n\u003cp\u003eSTRUCTURE\u003c\/p\u003e\n\n\u003cp\u003eMolecular Formula: C₄₀₀H₆₂₅N₁₁₁O₁₁₅S₉\u003cbr\u003e\nMolecular Weight: 9117.5 g\/mol\u003cbr\u003e\nAmino Acid Sequence:\u003cbr\u003e\nMFPAMPLSSL FVNGPRTLCG AELVDALQFV CGDRGFYFNK PTGYGSSSRR APQTGIVDEC CFRSCDLRRL EMYCAPLKPA KSA\u003cbr\u003e\nCAS Registry Number: 946870-92-4\u003c\/p\u003e\n\n\u003cp\u003eCITATIONS\u003c\/p\u003e\n\n\u003cp\u003eAdipose Tissue-Derived Stem Cell Secreted IGF-1 Protects Myoblasts from the Negative Effect of Myostatin. Hindawi Journal.\u003cbr\u003e\nN. Li, Q. Yang, R. G. Walker, T. B. Thompson, M. Du, and B. D. Rodgers. Myostatin Attenuation In Vivo Reduces Adiposity, but Activates Adipogenesis. Endocrinology (2016).\u003cbr\u003e\nE. Corpas, S. M. Harman, and M. R. Blackman. Human growth hormone and human aging. Endocr. Rev. (1993).\u003cbr\u003e\nW. E. Sonntag, A. Csiszar, R. deCabo, L. Ferrucci, and Z. Ungvari. Diverse roles of growth hormone and insulin-like growth factor-1 in mammalian aging: progress and controversies. J. Gerontol. A. Biol. Sci. Med. Sci. (2012).\u003cbr\u003e\nIGF-I\/IGFBP system: metabolism outline and physical exercise. NCBI.\u003cbr\u003e\nB. Y. Hanaoka, C. A. Peterson, C. Horbinski, and L. J. Crofford. Implications of glucocorticoid therapy in idiopathic inflammatory myopathies. Nat. Rev. Rheumatol. (2012).\u003cbr\u003e\nA. Philippou, A. Halapas, M. Maridaki, M. Koutsilieris. Expression of IGF-1 isoforms after exercise-induced muscle damage in humans. J. Musculoskelet Neuronal Interact. (2007).\u003cbr\u003e\nA. Philippou, E. Papageorgiou, G. Bogdanis, A. Halapas. Characterization of the MGF E peptide actions in vitro. In Vivo (2009).\u003c\/p\u003e","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989560037609,"sku":"PS049-1","price":80.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/IGF-1-LR3-1mg-1.jpg?v=1778509456","url":"https:\/\/f1kjgr-r5.myshopify.com\/products\/igf-1-lr3-1mg","provider":"Peptides Verse","version":"1.0","type":"link"}