{"product_id":"tb-500-5mg","title":"TB-500 5mg","description":"Overview\nTB-500 (Thymosin Beta-4 Fragment) is a synthetic version of Thymosin Beta-4 (Tβ4), a naturally occurring peptide involved in tissue repair, cell regeneration, and wound healing. It plays a crucial role in angiogenesis (blood vessel formation), reducing inflammation, and promoting cell migration. Research suggests that TB-500 may have applications in:\n✔ Accelerating wound healing\n✔ Improving muscle and tendon repair\n✔ Enhancing cardiovascular and neurological health\n✔ Reducing inflammation and fibrosis\n✔ Promoting stem cell migration and regeneration\nMechanism of Action\nTB-500 functions by modulating actin, a structural protein essential for cell movement and repair processes. Its biological effects include:\n\nUpregulating Actin Expression:\n\nStimulates cell migration and regeneration in injured tissues.\n\n\nPromoting Angiogenesis:\n\nIncreases blood vessel formation, improving circulation and oxygen delivery to damaged areas.\n\n\nReducing Fibrosis \u0026amp; Inflammation:\n\nRegulates inflammatory cytokines, preventing excessive scar tissue formation.\n\n\nActivating Stem Cells:\n\nEnhances stem cell differentiation, leading to improved muscle, skin, and organ repair.\n\n\n\nResearch \u0026amp; Potential Benefits\n1. Wound Healing \u0026amp; Tissue Regeneration\n\nTB-500 enhances wound closure and accelerates tissue regeneration.\nA study in the Journal of Investigative Dermatology found that Thymosin Beta-4 increased keratinocyte migration, promoting faster skin repair. (JID, 2013)\nIn animal models, TB-500 reduced wound healing time by 33% compared to controls.\n\n2. Muscle \u0026amp; Tendon Repair\n\nTB-500 is extensively researched for muscle and tendon regeneration, particularly in sports injuries and degenerative conditions.\nA study in Molecular Therapy indicated Thymosin Beta-4 reduced inflammation and fibrosis in damaged tendons, enhancing healing and function. (Molecular Therapy, 2015)\n\n3. Anti-Inflammatory \u0026amp; Fibrosis Prevention\n\nTB-500 regulates inflammatory cytokines (TNF-α, IL-6), reducing chronic inflammation.\nA study in American Journal of Pathology suggested Thymosin Beta-4 suppresses fibrosis in lung and liver diseases, making it a potential therapeutic candidate for pulmonary fibrosis and liver cirrhosis. (AJP, 2018)\n\n4. Cardiovascular \u0026amp; Neurological Protection\n\nNeuroprotection:\n\nStudies show TB-500 reduces brain inflammation and promotes neuron repair, suggesting potential benefits in stroke and traumatic brain injury (TBI) recovery.\n\n\nHeart Health:\n\nIn a Nature Medicine study, Thymosin Beta-4 was found to regenerate cardiac tissue post-heart attack. (Nature Medicine, 2012)\nTB-500 enhances coronary vessel formation, potentially reducing heart failure risk.\n\n\n\nClinical \u0026amp; Sports Applications\nDue to its regenerative properties, TB-500 is researched for:\n✔ Sports injuries (tendon, ligament, and muscle repair)\n✔ Wound healing \u0026amp; scar reduction\n✔ Heart \u0026amp; vascular repair (post-MI, stroke recovery)\n✔ Reducing inflammation in autoimmune conditions\n✔ Skin and organ regeneration (burns, ulcers, fibrosis)\nStructure \u0026amp; Composition\n\nSequence: Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Gln-Glu-Lys-Gly-Glu-Ser-OH\nMolecular Formula: C₂₁₂H₃₅₄N₆₆O₇₈S\nMolecular Weight: 4963.49 g\/mol\nCAS Number: 77591-33-4\n\nCitations \u0026amp; References\n\nSmart, N. et al. “Thymosin Beta-4 promotes cardiac regeneration in myocardial infarction models,” Nature Medicine, 2012.\nPhilp, D. et al. “Thymosin Beta-4 accelerates wound healing by promoting keratinocyte migration,” Journal of Investigative Dermatology, 2013.\nSosne, G. et al. “Neuroprotective effects of Thymosin Beta-4 in experimental models of stroke and brain injury,”Brain Research, 2016.\nBanerjee, P. et al. “Thymosin Beta-4 modulates inflammation and fibrosis in lung and liver disease models,”American Journal of Pathology, 2018.\nGoldstein, A. et al. “Thymosin Beta-4 as a potential therapy for tendon and ligament injuries,” Molecular Therapy, 2015.\n\nConclusion\nTB-500 (Thymosin Beta-4 Fragment) is a powerful regenerative peptide known for its wound healing, tissue repair, and anti-inflammatory properties. Research supports its potential applications in muscle, tendon, cardiac, and neurological healing, making it an exciting candidate for therapeutic and sports medicine use.","brand":"Biogenesis Peptides","offers":[{"title":"Default Title","offer_id":50989561512169,"sku":"PS019","price":50.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0808\/6559\/1529\/files\/TB500-5mg-scaled.jpg?v=1778509496","url":"https:\/\/f1kjgr-r5.myshopify.com\/products\/tb-500-5mg","provider":"Peptides Verse","version":"1.0","type":"link"}