Molecular Weight: ~340 Da | Sequence: Gly-His-Lys | Form: Lyophilized | Purity: 99%+ HPLC
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring copperbinding tripeptide first isolated from human plasma albumin by Loren Pickart in 1973. In preclinical and in vitro research models, GHK-Cu has been documented to modulate the expression of over 4,000 human genes, stimulate collagen I and III synthesis in fibroblast cultures, upregulate VEGF-mediated angiogenesis, and interact with antioxidant enzyme pathways including SOD and catalase. Each vial contains 100mg of lyophilized GHK-Cu at 99%+ HPLC-verified purity, with a batch-specific Certificate of Analysis available for download. *
View Compound Facts
GHK-Cu 100mg · Lyophilized Powder · 3mL Glass Vial · Copper Tripeptide-1| Parameter | Detail |
|---|---|
| Compound | GHK-Cu (Copper Tripeptide-1) |
| Full Name | Glycyl-L-Histidyl-L-Lysine Copper Complex |
| Amount Per Vial | 100mg |
| Purity | ≥99% by HPLC |
| Amino Acid Sequence | Glycine → Histidine → Lysine |
| Copper Binding | Cu²⁺ chelated form (redox-silent) |
| Molecular Formula | C₁₄H₂₂CuN₆O₄ |
| Molecular Weight | ~403 Da |
| CAS Number | 49557-75-7 |
| Form | Lyophilized Powder |
| Vial Size | 3mL glass vial |
| Fillers / Additives | None |
| Preservatives | None |
| Testing Method | HPLC + LC-MS |
| Tested By | Independent Third-Party Laboratory |
| Batch COA | Available for download — batch-specific |
| SDS | Safety Data Sheet available on request |
What it does not contain
Storage & Handling
Store lyophilized powder at –20°C upon receipt. Protect from light and moisture. Keep in original sealed vial until research use. Handle with appropriate PPE in a controlled laboratory environment.
FEATURED INGREDIENTS
Lysine
Essential amino acid that supports collagen production.
Proline
Supports skin, joints and connective tissue.
Valine
Supports muscle recovery and energy production.
All Ingredients
Lysine
Essential amino acid that supports collagen production, skin repair, and tissue growth.
Proline
Improves skin elasticity, strengthens joints, and supports connective tissue health.
Valine
Helps muscle recovery, boosts energy production, and improves exercise endurance.
PRODUCT BENEFITS
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Collagen Synthesis Modulation GHK-Cu stimulates TGF-β signaling and upregulates collagen I and III gene expression in fibroblast culture models. Preclinical studies document selective stimulation of collagen secretion without altering non-collagen protein synthesis.
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VEGF-Driven Angiogenesis Research Research models show GHK-Cu upregulates vascular endothelial growth factor (VEGF) expression, promoting new capillary formation—a key parameter in wound bed perfusion and tissue repair studies.
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Antioxidant Enzyme Pathway Studies GHK-Cu has been studied for interactions with superoxide dismutase (SOD), catalase, and glutathione pathways. In vitro data documents modulation of TNF-α, IL-6, and COX-2 inflammatory cytokine expression.
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Broad Gene Expression Modulation Bioinformatics analyses by Pickart et al. document GHK-Cu modulating over 4,000 human genes—approximately 6% of the human genome. A significant subset relates to extracellular matrix maintenance and collagen production.
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99%+ HPLC-Verified Purity Every batch of GHK-Cu is independently verified by third-party analytical laboratories using HPLC and LC-MS. Batch-specific COA and SDS are available before purchase with no hidden formulations.
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Lyophilized for Research-Grade Stability Supplied as lyophilized powder in a 3mL glass vial for maximum long-term stability. Lyophilization removes moisture that accelerates peptide degradation, helping maintain compound integrity throughout the research lifecycle.
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GHK-Cu is a tripeptide-copper complex (Gly-His-Lys chelated to Cu² ) that is posited to function as an extracellular damage signal. At sites of tissue disruption, plasma GHK-Cu concentrations are known to rise, activating a cascade of repair-associated cellular responses.*
WHAT TO EXPECT
Traceable ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable Ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable Ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable Ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable ingredients
Third-party tested
10+ years of expertise
Designed for women
Traceable Ingredients
Third-party tested
10+ years of expertise
Designed for women
Lysine
Essential amino acid that supports collagen production, tissue repair, immune function, and calcium absorption.*
Proline
Key building block of collagen that helps maintain healthy skin, connective tissue, joints, and wound healing.*
Valine
Branched-chain amino acid (BCAA) that supports muscle recovery, energy production, and tissue regeneration.*
All Ingredients
- Lysine — Supports collagen production, tissue repair, immune function.
- Proline — Helps maintain skin, joints, and wound healing.
- Valine — Supports muscle recovery and energy production.
- Additional Ingredient — Add your custom detail here.
The "KPV" Peptide |
No fillers | No artificial additives | No excipients | No repackaged imports | No human-use claims |
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KPV Peptide
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Other Peptide
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The "KPV" Peptide
| Compare to: |
KPV Peptide
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Other Peptide
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| No fillers | ||
| No artificial additives | ||
| No excipients | ||
| No repackaged imports | ||
| No human-use claims |
FAQs
GHK-Cu (Glycyl-L-Histidyl-L-Lysine Copper Complex) is a naturally occurring copper-binding tripeptide studied extensively in preclinical and in vitro research models. It is primarily researched for its role in tissue repair, collagen synthesis, wound healing, gene expression modulation, hair follicle biology, and antioxidant defense pathways.
Lyophilized means the compound has been freeze-dried — water is removed under vacuum to produce a stable powder. This process significantly extends shelf life and preserves compound integrity during storage and shipping. Lyophilized peptides are the research-grade standard because they maintain purity far longer than liquid formulations.
Each batch of GHK-Cu is independently verified at ≥99% purity using HPLC (High-Performance Liquid Chromatography). Identity is further confirmed by LC-MS (Liquid Chromatography-Mass Spectrometry). A batch-specific Certificate of Analysis (COA) is available for download before purchase.
Store lyophilized GHK-Cu at −20°C upon receipt. Keep protected from light, heat, and moisture. Do not open the vial until needed for your research protocol. Under proper storage conditions, lyophilized GHK-Cu maintains compound integrity for up to 24 months.
No. Peptides Verse does not provide reconstitution, dosing, or administration guidance of any kind. All reconstitution protocols are the sole responsibility of the qualified researcher or institution receiving this compound. This product is strictly for in vitro and laboratory research use only.
Yes. A batch-specific COA is available for every vial of GHK-Cu sold by Peptides Verse. The COA includes HPLC purity data, LC-MS identity confirmation, lot number, and testing lab details. It can be downloaded directly from the product page before or after purchase.
GHK refers to the free tripeptide (Glycyl-L-Histidyl-L-Lysine) without copper. GHK-Cu is the copper-chelated form — where a Cu² ion is bound to the tripeptide. The copper-chelated form is the biologically active version studied in most published research on wound healing, collagen synthesis, and gene expression modulation.
No. GHK-Cu from Peptides Verse is strictly for in vitro research and laboratory experimentation only. It is not intended for human or animal use of any kind. By purchasing, the buyer confirms they are a qualified researcher or institution and accepts full responsibility for safe handling and use.
All orders are shipped via FedEx with temperature-appropriate packaging to protect compound integrity during transit. Packaging is discreet — plain FedEx or UPS with no product branding on the exterior. Orders placed before 2 PM EST ship same business day.
Due to the nature of research chemicals, all sales are final once a vial has been opened or the seal broken. If you receive a damaged or incorrect item, contact support@peptidesverse.com within 48 hours of delivery with your order number and photos.